Phthisis Bulbus describes a “shrunken” eye, typically as a result of severe and/or chronic intraocular inflammation, infection, aqueous humor leakage and/or trauma. Clinically, affected globes are blind and may display reduced size, corneal fibrosis, uveal adhesions, cataracts and/or retinal detachment. Both canine and feline species of any breed or crossed breed may be affected.