The term ophthalmoplegia describes a syndrome of neurological deficits arising as a result of damage to the oculomotor nerve (CN III) and/or its nucleus. CN III normally provides somatic efferent innervation to the dorsal, medial & ventral rectus and ventral oblique muscles of the eye, as well as the levator palpebral muscle. This nerve also contains the parasympathetic fibers, which innervate the pupillary muscles.The superficial location of the parasympathetic fibers results in internal ophthalmoplegia being the most common clinical presentation. Ophthalmoplegia frequently results from a lesion affecting CN III at the level of the cavernous venus sinus (so called “cavernous sinus syndrome”). Additional symptoms, depending on site the site of the lesion may include reduced corneal and/or facial sensation as a result of impaired trigeminal nerve function and/or neurogenic KCS.