Golden Retriever Uveitis and Glaucoma

A syndrome comprising slowly progressive intraocular changes, typically culminating in secondary glaucoma, is well recognized within the Golden Retriever breed. This syndrome has been variably described as “Pigmentary Uveitis”, “Golden Retriever Uveitis” and “Pigmentary & Cystic Glaucoma of Golden Retrievers”. Findings may include any combination of conjunctival and/or episcleral hyperemia, corneal decompensation, thin-walled uveal cysts within the anterior or posterior chambers, proteinaceous exudation within the anterior chamber, anterior and/or posterior iridal adhesions, pigment dispersion within the anterior chamber and/or onto the anterior lens capsule, cataract formation, hyphema and/or secondary glaucoma. Uveal cysts may detach and move into the anterior chamber where they may rupture against corneal endothelial and/or iridal surfaces or collapse and rupture within the iridocorneal angle. The hallmark of this syndrome has been described as the appearance of pigment on the anterior lens capsule, typically distributed in a radial orientation.