Corneal ulceration may arise secondary to a multitude of etiologies including conformational abnormalities, tear-film deficiencies (quantitative and/or qualitative), neurological dysfunction, trauma and/or microbial contamination.
Bacterial keratitis should be treated using appropriate antimicrobial therapy. In cases of deep stromal ulceration, or those associated with existing or impending corneal rupture, surgical tectonic corneal grafting may be indicated.