COLLIE EYE ANOMALY (CEA)


Collie Eye Anomaly describes a, congenital, hereditary disease resulting from abnormal embryonic differentiation of ocular tissues. Changes may include any combination of choroidal vascular hypoplasia, retinal pigment epithelial (RPE) and/or tapetal defects, abnormal retinal vasculature, scleral colobomas (typically involving the region surrounding the optic nerve head), retinal dysplasia and/or retinal detachment (partial or complete). Changes are bilateral but not always symmetrical. Most affected animals are clinically asymptomatic, abnormalities only being detected upon fundic examination, however, patients may present as a result of symptoms associated with retinal detachment and/or hyphema. Commonly affected breeds include the Collie breeds, Australian Shepherd & Shetland Sheepdog.